A biophysically detailed simulation of the whole mouse cortex neuron by neuron, with sub-cellular resolution (IMAGE)

Allen Institute

A biophysically detailed simulation of the whole mouse cortex neuron by neuron, with sub-cellular resolution

Caption

Biophysically detailed simulation of the whole mouse cortex neuron by neuron, with sub-cellular resolution—that is, capturing ion flows and fluctuations of membrane voltage within many compartments that the tree-like neuronal morphologies consist of. Neurons are colored by cortical area and marked with a light flash when active. Only 1% of neurons are shown for clarity. The simulation represents “spontaneous” activity of the cortex in a resting state.

Credit

Barry Isralewitz1, with contributions by Kaaya Akira-Tamura2, Kael Dai3, Laura Green3, Beatriz Herrera3, Tadashi Yamazaki2, and Anton Arkhipov3 using the simulation from the paper.

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