SCHEMATIC ILLUSTRATION OF MONO-TO-IM TRANSITION DURING RICIN-INDUCED DAD (IMAGE)

Higher Education Press

SCHEMATIC ILLUSTRATION OF MONO-TO-IM TRANSITION DURING RICIN-INDUCED DAD

Caption

Lethal ricin inhalation will induce the development of 2 distinct IM subsets, namely IMpi and IMai, from recruited Monopi in the DAD lung. Notably, a subset of recruited Monopi, designated pMonopi, can get the proliferating phenotype, and meanwhile serve as the intermediate of Monopi-to-IMai transition. GDF15 facilitates Monopi-to-pMonopi-to-IMai transition.

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HIGHER EDUCATON PRESS

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