PDAC tumor organoids (IMAGE)

Cold Spring Harbor Laboratory

PDAC tumor organoids

Caption

CSHL’s Krainer lab has discovered a key oncogenic circuit driving aggressive pancreatic ductal adenocarcinoma (PDAC) progression. Using human PDAC tumor organoids, seen here, the team developed a potential RNA splicing-based therapeutic that collapses the circuit.

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Krainer lab/CSHL

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