A Two-Step CRISPR-Based Approach for Full-Length Gene Humanization in Mice (IMAGE)

The Institute of Medical Science, The University of Tokyo

A Two-Step CRISPR-Based Approach for Full-Length Gene Humanization in Mice

Caption

TECHNO: A two-step genome editing strategy that enables efficient replacement of entire mouse loci with full-length human genes to generate gene-humanized mice.

Credit

Dr. Manabu Ozawa from The University of Tokyo, Japan

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