Figure 4. Pipelines for different strategies by rational design. (IMAGE)

Nanjing Agricultural University The Academy of Science

Figure 4. Pipelines for different strategies by rational design.

Caption

A (L398I), B (L509I), and C (T338S), controlling chemo-/regio-selectivity of CYP72A63 for rare licorice triterpenoids production [83]; D, rational design of CYP87D20 with evolutionary information for biosynthesis of mogrol precursor [85]; E, rational design of HCinS with dynamics simulation for various products [86]; F, rational design of CYP728B70 based on energy virtual screening for dehydroabietic acid synthesis [87].

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