UBL3-mediated sorting of proteins into small extracellular vesicles (IMAGE)

Fujita Health University

UBL3-mediated sorting of proteins into small extracellular vesicles

Caption

A conceptual illustration showing how ubiquitin-like 3 (UBL3) modification acts as a molecular “tag” that directs selected proteins into small extracellular vesicles (sEVs). Inside the secreting cell, UBL3-modified proteins are packaged into multivesicular bodies and released as sEVs, which then travel to and interact with recipient cells, enabling cell-to-cell communication.

Credit

Kunihiro Tsuchida, Fujita Health University, Japan

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