Image 1 (IMAGE)

National University of Singapore

Image 1

Caption

Schematic illustration of the one-step activation of native sugars followed by photocatalytic coupling with N-heteroarenes to deliver C-heteroaryl glycosides. The sugar compound is first selectively activated at the anomeric (C1) position, then exposed to an amine, a photocatalyst and visible light, allowing it to form a new carbon–carbon bond with a nitrogen-containing aromatic molecule. This streamlined process avoids many of the usually required protective steps.

Credit

Nature Synthesis

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NA

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