PTPB1 inhibitors in Alzheimer's disease (IMAGE)

Cold Spring Harbor Laboratory

PTPB1 inhibitors in Alzheimer's disease

Caption

The Tonks lab studied PTP1B inhibition in a mouse model of Alzheimer’s disease. When PTP1B was deleted, as shown in the bottom row, the brain’s immune cells (green) were better at engulfing harmful amyloid-β plaques (grey), as shown in the left column.

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Tonks lab/CSHL

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