A machine learning-enabled single-round nucleic acid aptamer analysis method directly reveals the shared secondary structure of its interaction with the target (IMAGE)
Caption
Figure 1. Flowchart of the working principle of machine learning based on single-round nucleic acid aptamer screening sequences, including: deep learning of core sequences, machine learning analysis of secondary structures, truncation and optimization process, and molecular design driven by deep learning based on single-round screening sequences.
Credit
CCS Chemistry
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CC BY-NC