SNA illustration (IMAGE)

Northwestern University

SNA illustration

Caption

An artistic interpretation of a spherical nucleic acid (SNA) nanoparticle carrying HPV antigen (E7₁₁–₁₉) and CpG adjuvant DNA interacting with scavenger receptor A to facilitate cellular internalization. Display and N-terminal orientation of the HPV antigen on N-HSNAs enhance antigen-specific CD8⁺ T-cell responses and anti-tumor activity.

Credit

Image created by Connor Forsyth and Jake Cohen from the Mirkin Research Group/Northwestern University

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