Fig. 1 Effect of HELN on Macroscopic appearance of stomach and ulcer scoring in Aspirin induced Gastric ulcer injury in rats. (IMAGE)

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Fig. 1 Effect of HELN on Macroscopic appearance of stomach and ulcer scoring in Aspirin induced Gastric ulcer injury in rats.

Caption

Fig. 1 Effect of HELN on Macroscopic appearance of stomach and ulcer scoring in Aspirin induced Gastric ulcer injury in rats. (A) G1 (normal control) shows smooth, intact mucosa without visible lesions. G2 (ulcer control) shows multiple prominent hemorrhagic streaks and mucosal disruption. Treatment groups G3 (HELN 100 mg/kg), G4 (HELN 200 mg/kg), G5 (HELN 400 mg/kg), G6 (omeprazole) and G7 (sucralfate) show minimal mucosal damage with preserved surface integrity as compared to G2. (B) Ulcer scores based on gross examination (mean ± SEM, n = 6). One-way ANOVA followed by Dunnett's multiple comparison test was used. G2 shows a significantly higher score than G1 (###p < 0.001). All treatment groups (G3–G7) show significant reductions in ulcer scores compared to G2 (∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001).

Credit

Deepika Pandey, Shivani Ghildiyal

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