PAR1 Graphics (IMAGE)

University of California - San Diego

PAR1 Graphics

Caption

This diagram illustrates the two different responses triggered by PAR1. PAR1 can trigger inflammation when activated by thrombin (left) or protection when activated by APC (right). GRK5 and β-arrestin2 each play key roles in these processes, but in different ways depending on the activator.

Credit

UC San Diego Health Sciences

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