Mortality prediction performance of the modified Phoenix Sepsis Score and pediatric sepsis scores (IMAGE)
Caption
PSS+ is the modified Phoenix Sepsis Score. The Phoenix Sepsis Score 4-organ-system criterion (PSS-4), which is based on the cardiovascular, respiratory, coagulation and neurological organ systems, is used to identify organ damage and diagnose pediatric sepsis. The Phoenix Sepsis Score 8-organ-system (PSS-8) is an expanded score based on the 8-organ-system model (adding the endocrine, immunological and renal organ systems to the PSS-4). The pediatric sequential organ failure assessment (pSOFA) score was developed by adapting the original SOFA score with age-adjusted cutoffs for organ-specific subscores. The pSOFA is calculated on the basis of 6 component organ system scores (respiratory, coagulation, hepatic, cardiovascular, neurological and renal). This figure compares the performance of the PSS+ with that of other pediatric sepsis scores and criteria for predicting mortality in children with suspected infection admitted to intensive care in the first 24 hours. (A) and (B) show the AUROC and AUPRC values of the 4 types of criteria and scores. (C) shows the AUROC values of different healthcare resource site, sex, and age groups in the internal validation set and external validation set. (D) shows the AUPRC values. The higher-resource sites are observational sites in Beijing and Shanghai. The lower-resource site in the internal validation set is the observation site in Guizhou. The performance is presented both quantitatively with 95% confidence intervals and visually with a color heatmap. Shading indicates highest (darkest) to lowest (lightest) in each row.
Credit
Chinese Medical Journal
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