‘Transition state’ mechanism behind sugar transport into cells (IMAGE)
Caption
Without glucose (red) the hill is too high to climb and so the protein (grey) cannot easily change its path along the dashed line: The light is red. Just like in enzymes, we show that glucose has the highest affinity for the intermediate protein state (yellow), and so glucose binding (red) means the protein can take an easier path along the solid line to transport the sugar: The light is green. Image: Claudia Alleva/Stockholm University.
Credit
Claudia Alleva/Stockholm University
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