Hypertension Associated with the Risk of Extrahepatic Cancers in the Metabolic Dysfunction-associated Steatotic Liver Disease Population (IMAGE)
Caption
A total of 6,605 individuals with extrahepatic cancers were identified from a population of 103,652 patients with MASLD. Hypertension and the combination of hypertension and hyperglycemia were significantly associated with extrahepatic cancers. This association was further supported by the finding that metabolism-based treatments might be significantly linked to a protective role in the MASLD population. The association was observed in individuals with FIB-4 scores ≥ 1.3 among those aged 35 to 65 years and ≥2.0 among those aged over 65 years. Individuals with MASLD over 40 years of age may be recommended for extrahepatic cancer screening, especially those with hypertension and FIB-4 scores ≥ 1.3.
Credit
Lai Wei, Ming Yang, Shuangqing Gao
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License
CC BY-NC