Scientists Uncover Hidden Drug-binding Pocket in Cancer Protein, Highlighting the Power and Limitations of AI Drug Discovery (IMAGE)

The Mount Sinai Hospital / Mount Sinai School of Medicine

Scientists Uncover Hidden Drug-binding Pocket in Cancer Protein, Highlighting the Power and Limitations of AI Drug Discovery

Caption

Researchers at the Icahn School of Medicine at Mount Sinai discovered a previously hidden pocket on PKMYT1, a protein involved in controlling how cells grow and divide, that current AI tools and experiments had missed. Their findings potentially open a new route to more selective drug design. 

Credit

Herrington, et al., Journal of the American Chemical Society

Usage Restrictions

May only use within the context of this news.

License

Original content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.