Mechanism of exercise-induced musclin mitigating periprosthetic joint infection (IMAGE)
Caption
Schematic illustration showing how regular exercise stimulates skeletal muscle to secrete musclin, which binds to FPR2 on macrophages, triggering metabolic reprogramming and enhanced efferocytosis to alleviate implant infections.
Credit
Dr. Xinhua Qu and Dr. Bing Yue from Renji Hospital, Shanghai Jiao Tong University School of Medicine Image Source Link: https://doi.org/10.1016/j.jshs.2026.101143
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License
CC BY-NC-ND