Engineered bacterial vesicles restore the power of last-resort antibiotics (IMAGE)

Pusan National University

Engineered bacterial vesicles restore the power of last-resort antibiotics

Caption

Researchers developed extracellular vesicles carrying the bacterial peptide TimP and the antibiotic polymyxin B (PMB), creating a targeted drug delivery platform called PMB@TimP EVs. The vesicles reprogram multidrug-resistant Escherichia coli to become more vulnerable to PMB, allowing the antibiotic to work at lower doses.

Credit

Prof. Kwang-sun Kim from Pusan National University, Republic of Korea

Usage Restrictions

Cannot be reused without permission.

License

Original content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.