Study overview and analytical workflow. (IMAGE)

Beijing Institute of Technology Press Co., Ltd

Study overview and analytical workflow.

Caption

(A) Schematic flowchart depicting participant selection from the China Health and Retirement Longitudinal Study (CHARLS), including baseline (2011) and follow-up (2015) waves. (B) Geographic distribution of the CHARLS study population across 50 cities in China. (C) Illustration of the difference-in-differences (DiD) design evaluating the association between within-individual changes in HW exposure and biological age acceleration (BAA) from 2011 to 2015. (D) Transcriptomic analysis workflow integrating heatwave (HW)-related differentially expressed genes (DEGs) identified from liver tissue of aged mice and aging-related genes from the AgeAnno database.

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Dengyong Xu, Zhejiang University.

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