Toward effective therapeutic strategies for obesity-related sarcopenia (IMAGE)

University of Toyama

Toward effective therapeutic strategies for obesity-related sarcopenia

Caption

This study clarifies the role of a specific population of immune cells in the deterioration of muscle tissue in the context of obesity. Targeting transforming growth factor-beta 1 (TGF-β1) signaling in CD206+ M2 macrophages could represent a promising strategy for counteracting obesity-related muscle loss by enhancing muscle regeneration and improving mitochondrial function.

Credit

Distinguished Research Professor Kazuyuki Tobe from the University of Toyama

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