Role of interleukin (IL)-26 in epigenetic remodeling and promotion of immune evasion in colorectal cancer (IMAGE)

Juntendo University Research Promotion Center

Role of interleukin (IL)-26 in epigenetic remodeling and promotion of immune evasion in colorectal cancer

Caption

Researchers reveal how IL-26-driven epigenetic changes promote colorectal cancer immune evasion and immunotherapy resistance, suggesting IL-26–STAT1–BRD4 axis as a promising therapeutic target to enhance anti-PD-1 immunotherapy in colorectal cancer.

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Dr. Takumi Itoh from Juntendo University, Japan

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