Mechanisms That Inhibit the Trapping of Lipid Nanoparticles by the Walls of Hepatic Sinusoids (IMAGE)

Innovation Center of NanoMedicine

Mechanisms That Inhibit the Trapping of Lipid Nanoparticles by the Walls of Hepatic Sinusoids

Caption

A positively charged oligopeptide containing double-stranded PEG transiently coats the sinusoidal walls of the liver, thereby inhibiting the uptake of lipid nanoparticles. As a result, it is possible to avoid unnecessary protein expression in the liver.

Credit

Satoshi Uchida, Science Tokyo

Usage Restrictions

Only use for media coverage

License

Original content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.