A Summary of the Current Applications of TG and GE for Trait Enhancement in Farmed Animals (IMAGE)

Higher Education Press

A Summary of the Current Applications of TG and GE for Trait Enhancement in Farmed Animals

Caption

 (a) The number of studies focuses on trait enhancement (growth, disease resistance, and fatty acids) across taxa using TG and GE. (b) The number of species/breeds involved in each taxonomic class. (c) The Sankey diagram illustrates the proportion of studies focusing on different traits per taxon, and the target transgenes or innate genes are listed in the right column. csGH: coho salmon growth hormone; tiGH: tilapia growth hormone; ovGH: ovine growth hormone; ccGH: channel catfish growth hormone; mlGH: mud loach growth hormone; cgGH: Clarias gariepinus growth hormone; gcGH: grass carp growth hormone; gcFST: grass carp follistatin; pGH: porcine growth hormone; roGH: rohu growth hormone; rtGH: rainbow trout growth hormone; ssGH: Atlantic salmon growth hormone; mc4r: melanocortin-4 receptor; IGF2: insulin-like growth factor 2; mc3r: melanocortin-3 receptor; FBXO40: fox box protein 40; PRLR: prolactin receptor; LepR, leptin receptor; TGFβ2: growth factor-beta 2; cec: cecropin; cath: cathelicidin; PBD-2: porcine beta-defensin 2; hLF: human lactoferrin; FMDV-shRNA: small hairpin RNA targeting foot-and-mouth disease virus; mx: myxovirus; Lys: lysozyme; CF-17: synthetic cecropin B analog; SP110: SP110 nuclear body protein; HDAC6: histone deacetylase 6; NRAMP1: natural resistance-associated macrophage protein-1; ICP4: infected-cell polypeptide-4; AIV-shRNA: small hairpin RNA targeting avian influenza virus; CSFV-shRNA: small hairpin RNA targeting classical swine fever virus; PERV-shRNA: small hairpin RNA targeting porcine endogenous retrovirus; TSV-CP: taura syndrome virus coat protein; chIFITM3: chicken interferon-induced transmembrane 3; NHE1: chicken ALV-J receptor Na+/H+ exchanger type 1; ANPEP: amino peptidase N; EcoBCO2: β-carotene 9'/10'-oxygenase; EcNinaB: carotenoid isomerooxygenase; PCBP1: poly-binding protein 1; W38: amino acid tryptophan 38; D5D: delta5-desaturase; fat2: humanized Caenorhabditis elegans gene 2; G0S2: G0/G1 switch gene 2.

Credit

Jinhai Wang, Shinichi Nakagawa, Jiaqi Wang, Robert Stewart, Alexandra Florea, Rex A. Dunham, Fei Ling, Gaoxue Wang, Lily Liu, Diego Robledo

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