Solid-phase peptide synthesis-based design strategy and experimental facility for selenopeptide synthesis. (IMAGE)

Tsinghua University Press

Solid-phase peptide synthesis-based design strategy and experimental facility for selenopeptide synthesis.

Caption

Solid-phase peptide synthesis via 9-fluorenylmethoxycarbonyl strategy enables stepwise C-to-N assembly of selenopeptides on resin through repeated coupling, deprotection, and washing cycles, followed by cleavage. Nitrogen prevents selenium oxidation; vacuum filtration accelerates washing. The selenohydryl group of selenocysteine requires methoxybenzyl protection, whereas selenomethionine does not.

Credit

Food Science of Animal Products, Tsinghua University Press

Usage Restrictions

News organizations may use or redistribute this image, with proper attribution, as part of news coverage of this paper only.

License

Original content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.