Spatial transcriptomics (IMAGE)

Nagoya University

Spatial transcriptomics

Caption

Xenium spatial transcriptomics linked to nuclear morphometry shows that nuclear atypia correlates with rising oncogenic markers and falling homeostatic markers. Fe-NTA exposure generates three karyomegalic niches — quiescent (K1), adaptive (K4), and precancerous (K2) — reflecting distinct nuclear-to-transcriptional states.

Credit

Kong et al., Redox Biology 95 (2026) 104293, CC BY-NC-ND 4.0

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Credit must be given to the creator. Only noncommercial uses of the work are permitted. No derivatives or adaptations of the work are permitted.

License

CC BY-NC-ND

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