Meshwork-like condensates formed by the RNA-binding protein SFPQ and their function (IMAGE)

Ehime University

Meshwork-like condensates formed by the RNA-binding protein SFPQ and their function

Caption

Super-resolution image of meshwork-like condensates formed by SFPQ using RNA as a scaffold in neuronal nuclei (left; green, SFPQ; red, FUS), together with a schematic showing how these structures support extra-long gene expression in neurons and how their disruption may contribute to neurological disorders (right).

Credit

Akihide Takeuchi

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