CRISPR-assisted nanodroplet platform for multiplexed mycobacteria identification (IMAGE)

Shanghai Jiao Tong University Journal Center

CRISPR-assisted nanodroplet platform for multiplexed mycobacteria identification

Caption

Schematic overview of the CRISPR-Assisted Nanodroplet-pairing Platform for Differential Identification of NTM (CANDI). The platform combines broad-range amplification using conserved regions of the 16S and 23S rRNA genes with species-specific CRISPR recognition. Fluorescence-coded CRISPR droplets are paired with sample droplets containing amplified products, enabling multiplexed target recognition and signal decoding

Credit

Yiwen Yang, Jingsong Xu, Dakang Xu

Usage Restrictions

Credit must be given to the creator.

License

CC BY

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.