Overview of a rapid diagnostic workflow for fungal bloodstream infections (IMAGE)

Chiba University

Overview of a rapid diagnostic workflow for fungal bloodstream infections

Caption

Host DNA is selectively depleted from blood culture samples collected before the culture turns out positive, followed by fungal DNA extraction, PCR-based whole-genome amplification, and real-time nanopore sequencing. This method enables species-level identification within approximately seven hours, enabling earlier selection of appropriate antifungal treatment.

Credit

Professor Hiroki Takahashi and IMO, Chiba University, Japan

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