Figure 5 (IMAGE) Impact Journals LLC Caption Analysis of side population, sphere formation and TEAD reporter activity after TBID treatment in NSCLC cell lines. (A) Reduction of side population of human NSCLC A549 and H460 cell lines after TBID treatment. (B) Inhibition of secondary tumorsphere formation by TBID treatment in NSCLC cell lines. (C) TEAD reporter activity decreased in a dose-dependent manner in H460 cell line (p < 0.001, t-test). Error bars indicate standard deviations; ***p ? .001. (D) Schematic diagram of the potential differences in YAP/TEAD regulation between HIPK2 isoform 1 and isoform 3. Credit Correspondence to - Liang You - Liang.You@ucsf.edu Usage Restrictions Copyright: © 2021 Dai et al. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.