Figure 5: Biodistribution and flow cytometric analysis of DARA-DM1-IR in MM.1S IV mice. (IMAGE)
Caption
(A) Normalized biodistribution (defined as TMR) of DARA-DM1-IR, DARA-IR and IgG-IR 9 days after administration of fluorescent conjugate. n = 3–4/group. Two-way ANOVA followed by Sidak's multiple comparisons test was performed on biodistribution data. (B) Flow cytometric analysis of IRDye800 MFIs from excised bone marrow of DARA-DM1-IR, DARA-IR and IgG-IR-injected mice. One-way ANOVA followed by Tukey's multiple comparisons test was performed on flow cytometry data. n = 3–4/group. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001. Error bars represent standard deviation.
Credit
Correspondence to - Monica Shokeen - shokeenm@wustl.edu
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