Toxic DNA buildup in eyes may drive blinding macular degeneration (IMAGE)
Caption
New findings from UVA Health's Jayakrishna Ambati, MD, offer insights into how geographic atrophy progresses over time. “Although we’ve known that geographic atrophy expands over time, we didn’t know how or why,” said Ambati, of UVA’s Department of Ophthalmology and Center for Advanced Vision Science. “Our finding in human eyes that the levels of toxic Alu cDNA are highest at the leading edge of the geographic atrophy lesion provides strong evidence that it is responsible for this expansion over time that leads to vision loss.”
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K. Ambati
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May be used to accompany news coverage of the macular degeneration discovery. All other uses require express written permission from UVA Health.
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