Scheme of the new detection principle. (IMAGE)
Caption
Scheme of the new detection principle. A functionalized hydrogel microparticle (blue sphere) binds to the directionally immobilized enzyme (red) on a chip surface. Depending on the presence of estrogen-like compounds (gray spheres) in the detection solution, these bonds are blocked and the hydrogel microparticles become less deformed, which can be read out by optical methods.
Credit
Rettke et al
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Rettke et al
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