Single cell RNA-seq analysis of microglial response in a mouse model of Alzheimer’s disease. (IMAGE)

Weill Cornell Medicine

Single cell RNA-seq analysis of microglial response in a mouse model of Alzheimer’s disease.

Caption

Single cell RNA-seq analysis of microglial response in a mouse model of Alzheimer’s disease. Treatment with experimental drug MK2206 depleted a subcluster of disease-associated microglia (pink) and protected against synaptic loss (not pictured). Each dot depicts one microglial cell. Different colors depict different microglial states.

Credit

Image courtesy of Dr. Li Gan.

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