Hundreds of gene regulatory motifs cooperate and conflict to make brain cells (IMAGE)
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DNA is considered the blueprint of our human bodies. It codes for the tens of thousands of genes that determine whether a cell transforms into a brain cell, heart cell or even cancer cell. Other DNA sequences, known as enhancers, determine if genes are activated or inactivated. In a new study seen in Nature Communications, ASHBi Associate Professor Fumitaka Inoue and colleagues in the United States report the “massively parallel reporter perturbation assay” to study how enhancers are fine-tuned over time during the generation of brain cells.
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Kyoto University/stock.adobe.com
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