SNARE and Tomosyn (IMAGE)

Picower Institute at MIT

SNARE and Tomosyn

Caption

Above: Round vesicles carrying glutamate seek to dock to the cell membrane by binding to SNARE proteins (blue and yellow). In tonic neurons (left) tomosyn (brown and orange) intercepts the vesicles and binds them instead, preventing docking at the membrane, which is necessary for glutamate release across a synapse.

Credit

Littleton Lab/MIT PIcower Institute

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