Melanoma cell lines (IMAGE)

University of California - Los Angeles Health Sciences

Melanoma cell lines

Caption

Melanoma cell lines can harbor BRAF gene amplification (red signal) in two remarkably different modes, as extrachromosomal DNA (ecDNA) (left) and as an intrachromosomal homogeneously staining region (HSR) (right) after becoming resistant to MAPK inhibitors.

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Kai Song/UCLA

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