Increased DNA damage in neurons from SCA7 patients (IMAGE)

University of California - Irvine

Increased DNA damage in neurons from SCA7 patients

Caption

Increased DNA damage in neurons from SCA7 patients. Skin cells from an SCA7 patient and an unaffected sibling (WT), generated induced pluripotent stem cells. Those stem cells were used to make neurons which were grown in culture. Illustrated here are stained neurons with Hoechst to show the nucleus, and with ɣH2AX, which is a marker of DNA damage.

Credit

UCI School of Medicine

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