Aquaporin 5 (AQP5) deficiency can affect corneal nerve regeneration and the recovery of corneal sensitivity. (IMAGE)

Elsevier

Aquaporin 5 (AQP5) deficiency can affect corneal nerve regeneration and the recovery of corneal sensitivity.

Caption

(A) Staining for β-tubulin III in Aqp5+/+ and Aqp5-/- mice before and 48 hours after central corneal scraping. Images of the entire cornea are shown in the top panels, and central cornea images are shown in the bottom panels. Scale bars: 400 μm (bottom panels). (B) Nerve densities of the entire cornea (a, top panels) are calculated on the basis of the areas staining positive for β-tubulin III using Image J software (n=6). (C) Histogram of corneal sensitivity in Aqp5+/+ and Aqp5-/- mice before and 48 hours after central corneal scraping (n=6). uw, unwound; w, wound. *P < 0.05; **P < 0.01; ***P < 0.001.

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The American Journal of Pathology

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