PCP proteins regulate synapse numbers (IMAGE)
Caption
Image shows the localization and function of PCP proteins in regulating synapse numbers. Vangl2 causes synapse disassembly and Prickle antagonizes Vangl2 and promotes synapse stability. Fzd3: Frizzled3; PK: Prickle.
Credit
Zou lab, UC San Diego
Usage Restrictions
Must be used in conjunction with Science Advances paper on PCP synapse formation/maintenance.
License
Original content