Role of the STN as the coordinator of GPi neurons. (IMAGE)

National Institutes of Natural Sciences

Role of the STN as the coordinator of GPi neurons.

Caption

The STN stabilizes the activity of GPi neurons for smooth movements (yellow) in the normal state (left). The STN suppression induces unstable spike trains in the GPi (right). The variable spike trains during the movement lead to unstable movements (yellow). Increased spike train variability may increase the chance of coincident activity changes (green), resulting in involuntary movements.

Credit

Atsushi Nambu

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