In vitro-generated female germ cells entering meiosis in artificial ovary (IMAGE)
Caption
Image showing artificial ovary (left), where in vitro-generated female germ cells (magenta) enter meiosis (yellow cells) to become oocytes with the help from supporting cells (cyan). This process is four times more efficient when the X chromosome is correctly turned OFF and ON again during germ cell development. Also shown (top right) are oocytes at different maturation stages: from more immature on the left to more advanced on the right. Finally, the chromosomal organization during the meiosis process is shown (lower right) when germ cells become unique by reshuffling their genetic material.
Credit
Dr. Jacqueline Severino/CRG
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License
CC BY-NC