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National Institutes of Natural Sciences

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Caption

In Parkinson’s disease (PD), blockade of the movement signals originating from the primary motor cortex (M1) in the internal segment of the globus pallidus (GPi) causes movement difficulty. Conventional constant DBS (cDBS, left) applies electric stimulation continuously, unblocks the GPi, and enables movements. Newly developed adaptive DBS (aDBS, right) applies electric stimulation based on M1-γ2 band activity and unblocks the GPi when the movement signals reach the GPi.

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Atsushi Nambu

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