Fully assembled T-cell receptor (TCR) complex with a peptide/MHC ligand (IMAGE)
Caption
The cryo-EM structure of the fully assembled T-cell receptor (TCR) complex with a tumor-associated peptide/MHC ligand provides important insights into the biology of TCR signaling. These insights into the nature of TCR assembly and the unusual cell membrane architecture reveal the basis of antigen recognition and receptor signaling.
Credit
Robert Tampé, Goethe University Frankfurt
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