Adenovirus DNA transfer (IMAGE)

University of Zurich

Adenovirus DNA transfer

Caption

Incoming adenovirus particles (AdV) dock at the nuclear pore complexes of a human cell's nucleus (NPC, dashed line). The cellular enzyme Mind bomb1 (Mib1, grey-white structures) primes them for unlocking and removes protein V (GFP-V, green dots). The uncoated viral DNA genome is then imported into the nucleus. The arrow highlights a virus particle containing both protein V and Mib1, yellow denotes particles containing protein V, and red shows particles lacking V and Mib1.

Credit

Michael Bauer and Alfonso Gomez-Gonzalez, University of Zurich

Usage Restrictions

none

License

Original content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.