Illustration of DUBTAC targeting (IMAGE)

University of California Berkeley College of Chemistry

Illustration of DUBTAC targeting

Caption

DUBTACs are heterobifunctional molecules consisting of a protein-targeting ligand linked to a DUB recruiter via a linker. DUBTACs are ideally used for stabilizing the levels of actively ubiquitinated proteins that are degraded by the proteasome.

Credit

Courtesy of Nomura Lab

Usage Restrictions

Can be used in articles about this research.

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