Rhino re-localizes to the pericentromeric Satellite arrays upon Kipferl mutation or deletion (IMAGE)

IMBA- Institute of Molecular Biotechnology of the Austrian Academy of Sciences

Rhino re-localizes to the pericentromeric Satellite arrays upon Kipferl mutation or deletion

Caption

Two Drosophila egg chambers containing several nuclei: Wild Type (left) or upon Kipferl inactivation (right). The DNA is shown in blue and Rhino in green. Upon mutation or deletion of the partner protein Kipferl (right), Rhino loses its affinity for the piRNA cluster sequences across the genome (green dots in the left panel) but is sequestered by the pericentromeric Satellite arrays (green crescent-like shapes in the right panel). The crescent shapes inspired the name “Kipferl”, the name of an Austrian pastry.

Credit

©Baumgartner/Brennecke/IMBA

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