Working principle of SOAP, the lateral profile of OFUS, neurostimulation in vitro and in vivo. (IMAGE)

Light Publishing Center, Changchun Institute of Optics, Fine Mechanics And Physics, CAS

Working principle of SOAP, the lateral profile of OFUS, neurostimulation in vitro and in vivo.

Caption

A, an illustration of SOAP stimulating a neuron with an ultrasound focus delivered via the optoacoustic effect. B, the lateral profile of OFUS without and with presence of a piece of mouse skull. C, representative calcium images of cultured neurons before and after OFUS stimulation. The right panel shows the maximum ΔF/F. Scale bar: 50 µm. D, representative EMG recording of OFUS stimulation in mice. Orange box: laser on. E EMG signal after band-pass filter and full-wave rectifier and envelope.

Credit

by Yueming Li, Ying Jiang, Lu Lan, Xiaowei Ge, Ran Cheng, Yuewei Zhan, Guo Chen, Linli Shi, Runyu Wang, Nan Zheng, Chen Yang, Ji-Xin Cheng

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Credit must be given to the creator.

License

CC BY

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