Mechanism by which CREB-Regulated Transcription Coactivator 1 (CRTC1) suppresses overeating (IMAGE)
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Osaka Metropolitan University scientists have revealed that the transcription cofactor gene CRTC1 mediates the obesity-suppressing effects of melanocortin-4 receptor (MC4R) by regulating appetite for fats and oils, high-fat diet metabolism, and blood sugar.
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Shigenobu Matsumura, Osaka Metropolitan University
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