Early degradation of secretory granules in Drosophila larval salivary gland cells (IMAGE)

Eötvös Loránd University

Early degradation of secretory granules in Drosophila larval salivary gland cells

Caption

In their experiment, the researchers labelled the secretory granules of Drosophila salivary gland cells both green and magenta. Normally, the secretory granules are of the right size, are well separated from each other and contain both colours (image A). After the researchers knocked out the gene necessary for secretory granule maturation (image B), the secretory granules failed to reach their normal size, i.e. they were not of the right quality (the greenish-white spots in image B) and were prematurely diverted to the degradation pathway (the larger magenta spots in image B). In the figure, the nuclei are marked in blue.

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Photo: Tamás Csizmadia / Eötvös Loránd University

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