IAV replication in the presence or absence of MTr1: (IMAGE)

University of Bonn

IAV replication in the presence or absence of MTr1:

Caption

The host RNA is methylated by MTr1 to a mature cap1 RNA. The influenza virus snatches the cap part of the mature host RNA to start viral replication. MTr1-deficient cells or cells treated with MTr1 inhibitors do not lead to IAV replication.

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Image (created with BioRender.com): Yuta Tsukamoto/UKB

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